MSNBA is a potent and selective GLUT5 fructose transport inhibitor with an IC 50 of 0.10 mM. MSNBA does not affect the transport activity of human GLUT1 , GLUT2 , GLUT3 , GLUT4 or bacterial GlcPSe. MSNBA competitively inhibits GLUT5 fructose uptake with a K i of 3.2 μM in MCF7 cells. MSNBA can be used for the study of cancer or diabetes.
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