3-Hydroxymethyl-β-carboline

Overview

3-Hydroxymethyl-β-carboline is a Benzodiazepine antagonist with a K i value of ~1470 nM. 3-Hydroxymethyl-β-carboline reverses Flurazepam-induced sleep, cerebrovascular and cerebral metabolic inhibition, and also partially reverses Flurazepam-induced decreases in blood pressure and heart rate. 3-Hydroxymethyl-β-carboline disrupts the anticonvulsant and anxiolytic effects of Diazepam in male mice. 3-Hydroxymethyl-β-carboline has no effect on sodium-dependent high-affinity choline uptake in rat cortical or hippocampal synaptosomes.

Application

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Product Information

• Catalog No.: HY-W197533
• CAS No.: 65474-79-5
• Molecular Formula: C12H10N2O
• Molecular Weight: 198.22
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source