MAO-B-IN-46

Overview

MAO-B-IN-46 (Compound 16) is a selective hMAO-B inhibitor ( IC 50 : 26.8 nM), with weak activity against hMAO-A ( IC 50 : 7.2054 μM). MAO-B-IN-46 (Compound 8) also acts as an α-amylase inhibitor ( IC 50 : 19.46 μM). MAO-B-IN-46 exhibits certain neuroprotective effects and shows no significant toxicity to human gingival fibroblasts and SH-SY5Y cells. Additionally, MAO-B-IN-46 can scavenge DPPH and ABTS free radicals, with IC 50 values of 17.86 μM and 17.71 μM, respectively. MAO-B-IN-46 can be used in the research of neurodegenerative diseases such as Parkinson's disease, diabetes, and diseases related to oxidative stress resistance.

Application

Products | Products > Disease Areas > Metabolic or Endocrine Disease | Products > Disease Areas > Neurological, Eye or Ear Disease | Products > Disease Areas > Inflammation or Immune System Disease | Products > Signaling Pathways > Immunology/Inflammation | Products > Signaling Pathways > Neuronal Signaling | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Research Areas > Neurological Disease | Products > Research Areas > Metabolic Disease | Products > Research Areas > Inflammation/Immunology | Products > Signaling Pathways > Free Radical Scavengers | Products > Signaling Pathways > Monoamine Oxidase | Products > Signaling Pathways > Amylases

Product Information

• Catalog No.: HY-W207699
• CAS No.: 27052-20-6
• Molecular Formula: C15H9ClO2
• Molecular Weight: 256.68
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source