GCN2 activator-1

Overview

GCN2 activator-1 (Compound 20) is a GCN2 activator. GCN2 activator-1 binds within the ATP-pocket of GCN2 and activates GCN2 in a GCN1-independent manner. GCN2 activator-1 activates Integrated Stress Response ( ISR ) in cells. GCN2 activator-1 inhibits PKR with an IC 50 of 3.75 µM. GCN2 activator-1 can be used for research of pulmonary veno-occlusive disease (PVOD).

Application

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Product Information

• Catalog No.: HY-W319647
• CAS No.: 315705-10-3
• Molecular Formula: C11H10N6S2
• Molecular Weight: 290.37
• Purity: 99.69%
• Storage: Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
• Availability: In-stock

Source

Original product source