C1s-IN-1 trihydrochloride

Overview

C1s-IN-1 trihydrochloride (Compound A1) is the selective inhibitor for C1s protease with the K i of 5.8 μM. C1s-IN-1 trihydrochloride inhibits cleavage of C2 by C1s with an IC 50 of 85 μM, inhibits the activation of classic pathway with an IC 50 of 22 μM. C1s-IN-1 trihydrochloride is the competitive inhibitor for thrombin with the K i of 51.2 μM.

Application

Products | Products > Disease Areas > Inflammation or Immune System Disease | Products > Disease Areas > Autoimmune Disease | Products > Signaling Pathways > Immunology/Inflammation | Products > Research Areas > Inflammation/Immunology | Products > Signaling Pathways > Complement System

Product Information

• Catalog No.: HY-W371165
• CAS No.: 1376162-36-5
• Molecular Formula: C16H22Cl3N5
• Molecular Weight: 390.74
• Purity: 99.73%
• Storage: 4°C, sealed storage, away from moisture * In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
• Availability: In-stock

Source

Original product source