2'-O,4'-C-Methyleneguanosine

Overview

2′-O,4′-C-Methyleneguanosine (LNA-G) is a reverse guanine analog, where LNA (locked nucleic acid) is a nucleic acid analog. LNA modification can be widely used in various fields, such as effective binding affinity with complementary sequences and stronger nuclease resistance than natural nucleotides, providing great potential for application in disease diagnosis and research. 2'-O,4'-C-Methyleneguanosine is a substrate for KOD DNA polymerase , which incorporates LNA-G nucleotides into growing DNA strands, including consecutive incorporations , to generate full-length extension products.

Application

Products | Products > Disease Areas > Others | Products > Signaling Pathways > Cell Cycle/DNA Damage | Products > Research Areas > Others | Products > Signaling Pathways > Nucleoside Antimetabolite/Analog | Products > Signaling Pathways > DNA/RNA Synthesis

Product Information

• Catalog No.: HY-W406070
• CAS No.: 207131-16-6
• Molecular Formula: C11H13N5O5
• Molecular Weight: 295.25
• Purity: 99.22%
• Storage: 4°C, protect from light * In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
• Availability: In-stock

Source

Original product source