Cipargamin enantiomer

Overview

Cipargamin enantiomer (NITD609 enantiomer) is a Plasmodium falciparum inhibitor that can be characterized as a spirotetrahydro β-carboline (1S,3R stereoisomer). Cipargamin enantiomer exerts antiplasmodial activity against Plasmodium falciparum strains NF54 (IC 50 of 77 nM) and K1. Cipargamin enantiomer displays low liver microsomal intrinsic clearance in mouse and human systems. Cipargamin enantiomer does not inhibit CYP2C9 . Cipargamin enantiomer can be used for the research of malaria.

Application

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Product Information

• Catalog No.: HY-W413619
• CAS No.: 1193314-24-7
• Molecular Formula: C19H14Cl2FN3O
• Molecular Weight: 390.24
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source