Colestolone is a 15-ketosterol compound and an orally active inhibitor of HMG-CoA reductase . Colestolone can inhibit the activity of cholesteryl ester transfer protein ( CETP ) in vitro ( IC 50 = 660 μM). Colestolone is a cholesterol-lowering agent, and can be used in the research of endocrine and metabolic diseases such as hyperlipidemia.
Products | Products > Disease Areas > Metabolic or Endocrine Disease | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Research Areas > Metabolic Disease | Products > Signaling Pathways > HMG-CoA Reductase (HMGCR) | Products > Signaling Pathways > CETP
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