Valsartan methyl ester (Standard)

Overview

Valsartan (CGP 48933) methyl ester (Standard) is the analytical standard of Valsartan methyl ester ( HY-W414915 ). This product is intended for research and analytical applications. Valsartan methyl ester is the methyl ester derivative of Valsartan ( HY-18204 ). Valsartan is a selective angiotensin II type 1 (AT1) receptor blocker (ARB) with potent antihypertensive and cardioprotective effects. Valsartan competitively binds to AT1 receptors, inhibiting the binding of angiotensin II to AT1 receptors, thereby blocking angiotensin II-mediated vasoconstriction, sodium retention, and myocardial hypertrophy signaling pathways. Valsartan reduces systolic blood pressure in L-NAME-induced hypertensive rats. Valsartan can be used for the study and treatment of arterial hypertension, hypertensive heart disease, and heart failure.

Application

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Product Information

• Catalog No.: HY-W414915R
• CAS No.: 137863-17-3
• Molecular Formula: C25H31N5O3
• Molecular Weight: 449.55
• Purity: 98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.
• Availability: In-stock

Source

Original product source