SCH-23390 maleate

Overview

SCH-23390 maleate (R-(+)-SCH-23390 maleate) is a potent and selective dopamine D 1 -like receptor antagonist with K i s of 0.2 nM and 0.3 nM for the D 1 and D 5 receptor , respectively. SCH-23390 maleate is a potent and high efficacy human 5-HT 2C receptor agonist with a K i of 9.3 nM. SCH-23390 maleate also binds with high affinity to the 5-HT 2 and 5-HT 1C receptors . SCH-23390 maleate inhibits G protein-coupled inwardly rectifying potassium (GIRK) channels with an IC 50 of 268 nM.

Application

Products | Products > Disease Areas > Neurological, Eye or Ear Disease | Products > Signaling Pathways > GPCR/G Protein | Products > Signaling Pathways > Neuronal Signaling | Products > Signaling Pathways > Membrane Transporter/Ion Channel | Products > Research Areas > Neurological Disease | Products > Signaling Pathways > Dopamine Receptor | Products > Signaling Pathways > 5-HT Receptor | Products > Signaling Pathways > Potassium Channel

Product Information

• Catalog No.: HY-108400
• CAS No.: 87134-87-0
• Molecular Formula: C21H22ClNO5
• Molecular Weight: 403.86
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source