Probucol dithiobisphenol (DTBP) is the derivative of Probucol ( HY-B0388 ). Probucol dithiobisphenol induces the production of heme oxygenase 1 ( HO-1 ), and exhibits antioxidant activity. Probucol dithiobisphenol inhibits atherosclerotic lesions in Apoe −/− mice aorta, promotes re-endothelialization of aorta and inhibits restenosis in rabbit arterial injury models. Probucol dithiobisphenol is orally active.
Products | Products > Disease Areas > Blood or Cardio-cerebrovascular Disease | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Research Areas > Cardiovascular Disease | Products > Signaling Pathways > Heme Oxygenase (HO)
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