Melicopine

Overview

Melicopine is an alkaloid found in Z. simulans with antimalarial and anticancer activities. It exhibits inhibitory activity against chloroquine-sensitive 3D7 and chloroquine-resistant Dd2 strains of P. falciparum , with IC 50 values of 29.7 and 33.7 µg/mL, respectively. Melicopine is cytotoxic to prostate cancer cells PC-3M and LNCaP ( IC 50 values of 47.9 and 37.8 µg/mL), but has no effect on non-cancerous HEK293 cells ( IC 50 greater than 100 µg/mL). Melicopine holds promise for research in anticancer and anti-infection fields.

Application

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Product Information

• Catalog No.: HY-W437569
• CAS No.: 568-01-4
• Molecular Formula: C17H15NO5
• Molecular Weight: 313.30
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source