Nitrovin

Overview

Nitrovin (Difurazon) is a thioredoxin reductase 1 ( TrxR1 ) inhibitor with both antibacterial and anticancer activities. Nitrovin interacts with TrxR1 to generate reactive oxygen species ( ROS ), which in turn induces cytoplasmic vacuolization, activates MAPK and inhibits Alix . Nitrovin induces paraptosis-like non-apoptotic cell death, thereby exerting significant cytotoxicity against cancer cells. Nitrovin can be used in the research of heart disease and glioblastoma multiforme.

Application

Products | Products > Disease Areas > Cancer | Products > Disease Areas > Neurological, Eye or Ear Disease | Products > Disease Areas > Blood or Cardio-cerebrovascular Disease | Products > Disease Areas > CNS Neoplasm | Products > Disease Areas > Glioma | Products > Disease Areas > Heart Disease | Products > Disease Areas > Glioblastoma Multiforme | Products > Disease Areas > Glioblastoma Multiforme | Products > Signaling Pathways > Anti-infection | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Signaling Pathways > Apoptosis | Products > Signaling Pathways > MAPK/ERK Pathway | Products > Signaling Pathways > NF-κB | Products > Signaling Pathways > Immunology/Inflammation | Products > Research Areas > Neurological Disease | Products > Research Areas > Cardiovascular Disease | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Immunotherapy | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > Apoptosis | Products > Signaling Pathways > p38 MAPK | Products > Signaling Pathways > Reactive Oxygen Species (ROS) | Products > Signaling Pathways > Bacterial | Products > Signaling Pathways > TrxR

Product Information

• Catalog No.: HY-W504391
• CAS No.: 804-36-4
• Molecular Formula: C14H12N6O6
• Molecular Weight: 360.28
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source