PD 144418 oxalate is a highly affinity, potent and selective sigma 1 (σ1) receptor ligand ( K i values of 0.08 nM and 1377 nM for σ1 and σ2 respectively). PD 144418 oxalate devoids of any significant affinity for other receptors, ion channels and enzymes . PD 144418 oxalate shows potential antipsychotic activity.
Products | Products > Disease Areas > Neurological, Eye or Ear Disease | Products > Signaling Pathways > Neuronal Signaling | Products > Research Areas > Neurological Disease | Products > Signaling Pathways > Sigma Receptor
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