Thalidomide-NH-(CH2)3-NH-Boc

Overview

Thalidomide -NH-(CH2)3-NH-Boc is a Boc-modified Thalidomide ( HY-14658 ), which acts as a Cereblon ligand to recruit CRBN protein. The Boc protecting group at the end of Thalidomide -NH-(CH2)3-NH-Boc can be removed under acidic conditions to participate in the synthesis of PROTAC molecules. Thalidomide -NH-(CH2)3-NH-Boc is a key intermediate in the synthesis of CRBN-based designed PROTAC molecules targeting 11β-substituted estradiol.

Application

Products | Products > Disease Areas > Cancer | Products > Signaling Pathways > PROTAC | Products > Signaling Pathways > Autophagy | Products > Signaling Pathways > Apoptosis | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Research Areas > Cancer | Products > Signaling Pathways > E3 Ligase Ligand-Linker Conjugates | Products > Signaling Pathways > Autophagy | Products > Signaling Pathways > Apoptosis

Product Information

• Catalog No.: HY-W584515
• CAS No.: 2093386-36-6
• Molecular Formula: C21H26N4O6
• Molecular Weight: 430.45
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source