Thalidomide-5-O-CH2-COOH

Overview

Thalidomide -5-O-CH2-COOH is an E3 Ligase Ligand-Linker Conjugate consisting of Thalidomide ( HY-14658 ) and NH-PEG3-NH-Boc. Thalidomide -5-O-CH2-COOH acts as a ligand for Cereblon to recruit CRBN protein. Thalidomide -5-O-CH2-COOH is a key intermediate in the synthesis of PROTAC molecules designed based on CRBN.

Application

Products | Products > Disease Areas > Cancer | Products > Signaling Pathways > PROTAC | Products > Signaling Pathways > Autophagy | Products > Signaling Pathways > Apoptosis | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Research Areas > Cancer | Products > Signaling Pathways > E3 Ligase Ligand-Linker Conjugates | Products > Signaling Pathways > Autophagy | Products > Signaling Pathways > Apoptosis

Product Information

• Catalog No.: HY-W584518
• CAS No.: 2467425-53-0
• Molecular Formula: C15H12N2O7
• Molecular Weight: 332.26
• Purity: 95.02%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
• Availability: In-stock

Source

Original product source