XE991 dihydrochloride

Overview

XE991 dihydrochloride, a Kv7 (KCNQ) channels blocker, potently inhibits Kv7.1 (KCNQ1) , Kv7.2 (KCNQ2) , Kv7.2 + Kv7.3 (KCNQ3) channel, and M-current with IC 50 s of 0.75 μM, 0.71 μM, 0.6 μM, and 0.98 μM, respectively.

Application

Products | Products > Disease Areas > Neurological, Eye or Ear Disease | Products > Disease Areas > Neurodegenerative Disease | Products > Disease Areas > Alzheimer's Disease | Products > Signaling Pathways > Membrane Transporter/Ion Channel | Products > Research Areas > Neurological Disease | Products > Signaling Pathways > Potassium Channel

Product Information

• Catalog No.: HY-108577
• CAS No.: 122955-13-9
• Molecular Formula: C26H22Cl2N2O
• Molecular Weight: 449.37
• Purity: 99.98%
• Storage: 4°C, sealed storage, away from moisture * In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
• Solubility: ≥ 0.71 mg/mL (1.58 mM); Clear solution
• Availability: In-stock

Source

Original product source