Apafant-d 8

Overview

Apafant-d 8 is the deuterium labeled Apafant. Apafant (WEB 2086) is a potent platelet-activating factor (PAF) antagonist, inhibits PAF binding to human PAF receptors with a K i of 9.9 nM. Apafant increases the gene expression of PAF-r, α-globin, β-globin, decreases the c-myb gene expression. Apafant shows a protective effect on alkyl-PAF-mediated lethalit.

Application

Products | Products > Disease Areas > Inflammation or Immune System Disease | Products > Signaling Pathways > Others | Products > Signaling Pathways > GPCR/G Protein | Products > Research Areas > Inflammation/Immunology | Products > Signaling Pathways > Isotope-Labeled Compounds | Products > Signaling Pathways > Platelet-activating Factor Receptor (PAFR)

Product Information

• Catalog No.: HY-108634S
• CAS No.: 1185101-22-7
• Molecular Formula: C22H14D8ClN5O2S
• Molecular Weight: 464.01
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.
• Availability: In-stock

Source

Original product source