Panaxytriol is an active component of ginseng. Panaxytriol inhibits the nuclear translocation of NF-κB , thereby reducing the production of pro-inflammatory factors (such as TNF-α , IL-1β , IL-6 ) and nitric oxide ( NO ) induced by LPS ( HY-D1056 ). Panaxytriol upregulates CYP3A4 by activating the nuclear receptor PXR/CAR . Panaxytriol improves motor dysfunction in a mouse model of brain inflammation. Panaxytriol can be used in the research of neurodegenerative diseases (such as Alzheimer's disease).
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