Ponatinib hydrochloride

Overview

Ponatinib hydrochloride (AP24534 hydrochloride) is a hydrochloride of ponatinib. Ponatinib is an orally active multi-targeted kinase inhibitor with IC 50 s of 0.37 nM, 1.1 nM, 1.5 nM, 2.2 nM, and 5.4 nM for Abl , PDGFRα , VEGFR2 , FGFR1 , and Src , respectively.

Application

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Product Information

• Catalog No.: HY-108766
• CAS No.: 1114544-31-8
• Molecular Formula: C29H28ClF3N6O
• Molecular Weight: 569.02
• Purity: 99.76%
• Storage: 4°C, sealed storage, away from moisture * In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
• Solubility: ≥ 2.5 mg/mL (4.39 mM); Clear solution
• Availability: In-stock

Source

Original product source