O-Desmethyl-N-deschlorobenzoyl Indomethacin

Overview

O-Desmethyl-N-deschlorobenzoyl indomethacin is a metabolite of the non-steroidal anti-inflammatory drug (NSAID) and COX inhibitor indomethacin ( HY-14397 ). It is formed from indomethacin in isolated rabbit hepatocytes. O-Desmethyl-N-deschlorobenzoyl indomethacin (600 μM) decreases the viability of HL-60 leukemia cells when cultured with glucose oxidase. It has also been used in the synthesis of prostaglandin D2 ( HY-101988 ) receptor antagonists.

Application

Products | Products > Disease Areas > Inflammation or Immune System Disease | Products > Signaling Pathways > GPCR/G Protein | Products > Signaling Pathways > Immunology/Inflammation | Products > Research Areas > Inflammation/Immunology | Products > Signaling Pathways > Prostaglandin Receptor | Products > Signaling Pathways > COX

Product Information

• Catalog No.: HY-W740572
• CAS No.: 50995-53-4
• Molecular Formula: C₁₁H₁₁NO₃
• Molecular Weight: 205.21
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.
• Availability: In-stock

Source

Original product source