5-Hydroxy saxagliptin- 13 C,d 2 -2 hydrochloride is the 13 C- and deuterium labeled 5-Hydroxy saxagliptin hydrochloride. 5-Hydroxy saxagliptin hydrochloride is an active metabolite of Saxagliptin ( HY-10285 ) and a potent and selective DPP-4 inhibitor. 5-Hydroxy saxagliptin hydrochloride has K i values of 2.6 nM and 2.9 nM for humans and cynomolgus monkeys, respectively. 5-Hydroxy saxagliptin hydrochloride can be used in the research of type 2 diabetes mellitus.
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