Mizoribine 5'-monophosphate (MZR-P) is the active metabolite of Mizoribine ( HY-17470 ). Mizoribine 5'-monophosphate is an inhibitor of inosine-5'-monophosphate dehydrogenase ( IMPDH ), and its K i values for IMPDH of Trypanosoma brucei , Bacillus subtilis and Oceanobacillus iheyensis are 3.3, 72 and 157 nM respectively. Mizoribine 5'-monophosphate can be used in anti-trypanosomiasis and immunosuppression research.
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