Leu-AMS

Overview

Leu-AMS (compound 6), a leucine analogue, is a potent inhibitor of leucyl-tRNA synthetase ( LRS ) with an IC 50 of 22.34 nM, which inhibits the catalytic activity of LRS but did not affect the leucine-induced mTORC1 activation. Leu-AMS shows cytotoxicity in cancer cells and normal cells, and inhibits the growth of bacteria.

Application

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Product Information

• Catalog No.: HY-108900
• CAS No.: 288591-93-5
• Molecular Formula: C16H25N7O7S
• Molecular Weight: 459.48
• Purity: 99.57%
• Storage: Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
• Solubility: ≥ 2.5 mg/mL (5.44 mM); Clear solution
• Availability: In-stock

Source

Original product source