LYP-IN-1

Overview

LYP-IN-1 is a potent, selective and specific LYP inhibitor with a K i and an IC 50 of 110 nM and 0.259 μM, respectively. LYP-IN-1 also has selectivity for a large panel of PTPs, such as SHP1 ( IC 50 =5 μM) and SHP2 ( IC 50 =2.5 μM). LYP-IN-1 exhibits highly efficacious cellular activity in T- and mast cells. LYP-IN-1 can be used for the study of autoimmune disorders. LYP-IN-1 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

Application

Products | Products > Disease Areas > Inflammation or Immune System Disease | Products > Signaling Pathways > Protein Tyrosine Kinase/RTK | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Research Areas > Inflammation/Immunology | Products > Signaling Pathways > SHP1 | Products > Signaling Pathways > SHP2 | Products > Signaling Pathways > Phosphatase

Product Information

• Catalog No.: HY-108944
• CAS No.: 1404436-51-6
• Molecular Formula: C28H20ClNO6
• Molecular Weight: 501.91
• Purity: 99.82%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
• Availability: In-stock

Source

Original product source