5-POHSA is a CD36 and Src kinase modulator acting on taste bud cells, and belongs to the fatty acid esters of hydroxy fatty acids (FAHFA) family. 5-POHSA binds to lingual CD36 to initiate intracellular signaling pathways, activate downstream Src kinase, and rapidly elevate intracellular calcium levels. 5-POHSA interacts with the tongue-brain axis by binding to CD36 , so as to ameliorate taste disorders and obesity-related adverse reactions. 5-POHSA is applicable to the research of obesity.
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