Idebenone- 13 C,d 3

Overview

Idebenone - 13 C,d 3 is the deuterium labeled and 13 C-labeled Idebenone ( HY-N0303 ). Idebenone , a well-appreciated mitochondrial protectant, exhibits protective efficacy against neurotoxicity and can be used for the research of Alzheimer's disease, Huntington's disease. Idebenone (oxidised form) has a dose-dependent inhibitory effect on the enzymatic metabolism of arachidonic acid in astroglial homogenates (IC 50 =16.65 μM). Idebenone , a coenzyme Q10 analog and an antioxidant, induces apoptotic cell death in the human dopaminergic neuroblastoma SHSY-5Y cells. Idebenone quickly crosses the blood-brain barrier.

Application

Products | Products > Disease Areas > Neurological, Eye or Ear Disease | Products > Signaling Pathways > Others | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Signaling Pathways > Apoptosis | Products > Research Areas > Neurological Disease | Products > Signaling Pathways > Isotope-Labeled Compounds | Products > Signaling Pathways > Mitochondrial Metabolism | Products > Signaling Pathways > Apoptosis

Product Information

• Catalog No.: HY-W777283
• CAS No.: 1189907-75-2
• Molecular Formula: C1813CH27D3O5
• Molecular Weight: 342.45
• Purity: 99.62%
• Storage: -20°C, protect from light, stored under nitrogen * In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)
• Availability: In-stock

Source

Original product source