PD 124816

Overview

PD 124816 is an orally active fluoroquinolone antibiotic . PD 124816 exerts broad-spectrum antibacterial effects by inhibiting DNA gyrase ( topoisomerase IV ), and it has no cross-resistance with commonly used antibiotics . PD 124816 is effective against both Gram-positive and Gram-negative bacteria (MIC₉₀ ≤ 0.06 μg/mL), and the MIC₉₀ for anaerobic bacteria ( Peptostreptococcus fragi ) is 1 μg/mL. PD 124816 exhibits complete bactericidal activity in a mouse model of Mycobacterium leprae infection . PD 124816 can be used for studying mixed infections and infections caused by drug-resistant bacteria.

Application

Products | Products > Signaling Pathways > Anti-infection | Products > Signaling Pathways > Cell Cycle/DNA Damage | Products > Research Areas > Infection | Products > Signaling Pathways > Bacterial | Products > Signaling Pathways > Antibiotic | Products > Signaling Pathways > DNA/RNA Synthesis | Products > Signaling Pathways > Topoisomerase

Product Information

• Catalog No.: HY-W780694
• CAS No.: 112654-98-5
• Molecular Formula: C17H18F2N4O3
• Molecular Weight: 364.35
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source