Cryptolepine

Overview

Cryptolepine is an orally active multi-potent alkaloid with anti-cancer, anti-bacterial, anti-viral, anti-malarial, anti-inflammatory, anti-hyperglycemic, relieve pain and other properties. Cryptolepine acts as an inhibitor of c-Myc , mTOR , NF-κB , HIF-1, MAPK and an activator of AMPKα1/2 . It intercalates into DNA, inhibits topoisomerase II (Top II) , disrupts mitochondrial dynamics and induces apoptosis . Cryptolepine also exhibits anti-plasmodial and cholinesterase inhibitory activities. Cryptolepine can be used in research related to tumors (melanoma, hepatocellular carcinoma, mammary adenocarcinoma, etc.), malaria, inflammatory diseases and diabetes, particularly in studies focused on inhibiting tumor growth and anti-plasmodial infection .

Application

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Product Information

• Catalog No.: HY-W800535
• CAS No.: 480-26-2
• Molecular Formula: C16H12N2
• Molecular Weight: 232.29
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.
• Availability: In-stock

Source

Original product source