Pomalidomide 5'-pip-acid

Overview

Pomalidomide 5'-pip-acid is an E3 ligase ligand-linker conjugate derived from the molecular glue Pomalidomide ( HY-10984 ), which can be used to synthesize the dual-target PROTAC degrader PROTAC CBP/p300/BRD4 Degrader-1 ( HY-181758 ) targeting CBP/p300 and BRD4 . Pomalidomide 5'-pip-acid shows anti-proliferative activity against cancer cells with an IC 50 of 2.73 nM. Pomalidomide 5'-pip-acid induces anti-proliferative effects in cancer cells. Pomalidomide 5'-pip-acid is applicable to research related to prostate cancer and colorectal cancer .

Application

Products | Products > Disease Areas > Cancer | Products > Signaling Pathways > PROTAC | Products > Signaling Pathways > Others | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > E3 Ligase Ligand-Linker Conjugates | Products > Signaling Pathways > Drug Derivative

Product Information

• Catalog No.: HY-W877997
• CAS No.: 2467965-70-2
• Molecular Formula: C19H19N3O6
• Molecular Weight: 385.37
• Purity: 98.06%
• Storage: -20°C, protect from light, stored under nitrogen * In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)
• Availability: In-stock

Source

Original product source