CPDT is an orally active and highly potent inducer of phase 2 enzymes and an activator of Nrf2 . The activities of key phase 2 enzymes , including glutathione S-transferase , NAD(P)H:quinone:oxidoreductase 1 and glutamate cysteine synthetase, and levels of glutathione were elevated by CPDT in rat bladder in vivo and in cultured bladder cells in vitro[2].
Products | Products > Disease Areas > Neurological, Eye or Ear Disease | Products > Signaling Pathways > NF-κB | Products > Research Areas > Neurological Disease | Products > Signaling Pathways > Keap1-Nrf2
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