BPD is a COX-2 and TAK1-NF-κB inhibitor, with an IC 50 of 18.5 μM for COX-2 . BPD inhibits the expression of iNOS , TNF-α, IL-6 and IL-1β at the transcriptional level. BPD has anti-inflammatory activity. BPD can inhibit Carrageenan-induced paw oedema and LPS-induced septic death.
Products | Products > Disease Areas > Inflammation or Immune System Disease | Products > Signaling Pathways > Immunology/Inflammation | Products > Signaling Pathways > NF-κB | Products > Research Areas > Inflammation/Immunology | Products > Signaling Pathways > COX | Products > Signaling Pathways > NF-κB
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