Pizuglanstat hydrate (Compound 3; TAS-205) is an orally active prostaglandin D synthase inhibitor with an IC 50 of 76 nM for human hematopoietic prostaglandin D synthase . Pizuglanstat hydrate inhibits the synthesis of PGD 2 . Pizuglanstat hydrate improves experimental allergic rhinitis. Pizuglanstat hydrate can be used in the study of muscle regenerative diseases such as muscular dystrophy.
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