Sodium bromide

Overview

Sodium bromide (NSC 77384; Sanibrom 40) is a GABA -ergic system modulator that crosses the blood-brain barrier, and it effectively reduces and blocks epileptiform discharges. Sodium bromide exerts significant anticonvulsant effects by enhancing GABA -ergic inhibitory functions, such as increasing the amplitude of inhibitory postsynaptic currents and paired-pulse inhibition. Sodium bromide specifically enhances stimulation-induced extracellular alkalosis without affecting baseline pH or subsequent acidosis processes. Sodium bromide exhibits species-specific pharmacokinetic characteristics, competes with chloride ions for renal tubular reabsorption sites, and serves as a marker for extracellular fluid volume. Sodium bromide can be used in the research of epilepsy and related neurological diseases.

Application

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Product Information

• Catalog No.: HY-Y0282
• CAS No.: 7647-15-6
• Molecular Formula: BrNa
• Molecular Weight: 102.89
• Purity: 100.7%
• Storage: Store at room temperature, keep dry and cool. In solvent -80°C, 1 year , -20°C, 6 months
• Solubility: ≥ 3.33 mg/mL (32.36 mM); Clear solution
• Availability: In-stock

Source

Original product source