Hexane-2,5-dione

Overview

Hexane-2,5-dione (2,5-HD) is an orally active, CNS-penetrant cytotoxic agent . Hexane-2,5-dione reduces BCL-2 and β-catenin / TCF transcriptional activity, increases BAX and active caspase-3 expression, and promotes apoptosis . Hexane-2,5-dione causes an accumulation of neurofilaments within axons in rats. Hexane-2,5-dione can be used for the research of neurodegenerative diseases.

Application

Products | Products > Disease Areas > Neurological, Eye or Ear Disease | Products > Disease Areas > Neurodegenerative Disease | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Signaling Pathways > Apoptosis | Products > Signaling Pathways > Stem Cell/Wnt | Products > Signaling Pathways > Cell Cycle/DNA Damage | Products > Signaling Pathways > Cytoskeleton | Products > Research Areas > Neurological Disease | Products > Signaling Pathways > β-catenin | Products > Signaling Pathways > Caspase | Products > Signaling Pathways > Microtubule/Tubulin | Products > Signaling Pathways > Wnt | Products > Signaling Pathways > Drug Metabolite | Products > Signaling Pathways > Apoptosis | Products > Signaling Pathways > Bcl-2 Family

Product Information

• Catalog No.: HY-Y0315
• CAS No.: 110-13-4
• Molecular Formula: C6H10O2
• Molecular Weight: 114.14
• Purity: 99.96%
• Storage: Store at room temperature 3 years. In solvent -80°C, 2 years , -20°C, 1 year
• Solubility: ≥ 5 mg/mL (43.81 mM); Clear solution
• Availability: In-stock

Source

Original product source