Hexamethylphosphoramide

Hexamethylphosphoramide
  • CAS No.:680-31-9
  • Grade:99.86%
  • Formula:C6H18N3OP
  • M.W.:179.20

Overview

Hexamethylphosphoramide is an orally active polar aprotic solvent, flame retardant additive, and carcinogen. Hexamethylphosphoramide undergoes cytochrome P-450 -mediated N-demethylation to Formaldehyde. Hexamethylphosphoramide induces DNA-protein crosslinks . Hexamethylphosphoramide has been linked to nasal tumors (squamous cell carcinoma, adenoid squamous cell carcinoma), squamous metaplasia, rhinitis, tracheitis, and reversible and irreversible infertility.

Application

Products | Products > Disease Areas > Inflammation or Immune System Disease | Products > Disease Areas > Metabolic or Endocrine Disease | Products > Disease Areas > Cancer | Products > Signaling Pathways > Others | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Signaling Pathways > Cell Cycle/DNA Damage | Products > Research Areas > Inflammation/Immunology | Products > Research Areas > Endocrinology | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > Environmental Pollutants | Products > Signaling Pathways > Cytochrome P450 | Products > Signaling Pathways > Biochemical Assay Reagents | Products > Signaling Pathways > DNA Alkylator/Crosslinker

Product Information

  • Catalog No.: HY-Y1155
  • CAS No.: 680-31-9
  • Molecular Formula: C6H18N3OP
  • Molecular Weight: 179.20
  • Purity: 99.86%
  • Storage: Please store the product under the recommended conditions in the Certificate of Analysis.
  • Availability: In-stock

Source

Original product source


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