Cyclosporin A

Overview

Cyclosporin A (Cyclosporine A) is an immunosuppressant that binds to cyclophilins, inhibiting calcineurin activity with an IC50 of 7 nM. It also inhibits CD11a/CD18 adhesion molecules. Sequence: cyclo[Abu-Sar-N(Me)Leu-Val-N(Me)Leu-Ala-D-Ala-N(Me)Leu-N(Me)Leu-N(Me)Val-N(Me)Bmt(E)] Source summary: Cyclosporin A is a key immunosuppressive drug for transplant therapy. Inquire now for custom synthesis and fast delivery tailored to your requirements.

Application

Products > Drug Discovery > Inhibitor | Products > Drug Discovery > Inhibitor | Inflammation / Immunology | Cyclophilin

Product Information

• Catalog No.: B2695-300196
• CAS No.: 59865-13-3
• Molecular Formula: C62H111N11O12
• Molecular Weight: 1202.61
• Purity: 98%
• Storage: 4°C, protect from light
• Solubility: Soluble in Ethanol, Methanol, Chloroform, DMF, DMSO; Poorly soluble in Water

Source

Original product source