It is produced by the strain of Penicillum brevicompactum. It has weak anti-fungal activity and can inhibit the key enzyme (3-hydroxy-3-methyl glutaryl coenzyme A(HMGCoA) reductase) in the cholesterol biosynthesis pathway. It has been shown to lower cholesterol in animals and humans. It led the discovery of statins, lipid-lowering drugs. It is now used as a biochemical reagent.
Products > Drug Discovery > Inhibitor | Products > Drug Discovery > Inhibitor | Cardiovascular and blood system | HMG-CoA Reductase (HMGCR)
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