DMT-2'O-Methyl-rU Phosphoramidite is a 2'-O-methylated derivative utilized in the synthesis of oligonucleotides. Its primary mechanism involves the incorporation of 2'-O-methyluridine into RNA sequences, enhancing stability and reducing susceptibility to nucleases. This reagent is essential for applications in RNA synthesis, therapeutic development, and in the creation of modified nucleic acids for research studies.
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