5'-ODMT cEt N-Bz A Phosphoramidite (Amidite)

Overview

5'-ODMT cEt N-Bz A Phosphoramidite (Amidite) is a nucleoside phosphoramidite monomer utilized for the synthesis of locked nucleic acid (LNA) analog oligonucleotides. This compound enhances hybridization affinity and mismatch discrimination with RNA due to its 2',4'-constrained ethyl modification, which locks the furanose ring in an N-type conformation. Its properties significantly improve resistance to exonuclease digestion and facilitate the formation of stable RNA hybrids that can mediate RNase H-dependent mRNA degradation or inhibit translation. Applications include the development of antisense oligonucleotides for gene expression regulation, gene function research, and the synthesis of oligonucleotides for therapeutic interventions. - >99% HPLC purity, ideal for cancer research and epigenetic studies. Order now for fast global shipping and technical support.

Application

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Product Information

• Catalog No.: A55170
• CAS No.: 1197033-19-4
• Molecular Formula: C49H54N7O8P
• Molecular Weight: 899.97

Source

Original product source