YKL-06-061

Overview

YKL-06-061 is a small molecule serine/threonine-protein kinase SIK1 inhibitor (Ki = 6.56 nM) that is hopefully developed to be a dermatologic drug impacting UV protection and skin cancer risk. It causes a dose-dependent increase in microphthalmia-associated transcription factor (MITF) mRNA expression during 3-hour function in normal human melanocytes, UACC62 human melanoma cells, and UACC257 human melanoma cells.

Application

Products > Drug Discovery > Inhibitor | Products > Drug Discovery > Inhibitor | Cardiovascular and blood system | Salt-inducible Kinases (SIKs)

Product Information

• Catalog No.: B0084-112344
• CAS No.: 2172617-15-9
• Molecular Formula: C30H37N7O2
• Molecular Weight: 527.67

Source

Original product source