Erlotinib O-Desmethyl Metabolite Isomer (M14) HCl

Overview

OSI-420 (CP-473420) is an active metabolite of erlotinib which is an orally active EGFR tyrosin kinase inhibitor with IC50 of 2 and 20 nM for the inhibition of human EGFR and EGFR autophosphorylation in tumor cells.

Application

Products > Drug Discovery > Inhibitor | Products > Drug Discovery > Inhibitor | Cardiovascular and blood system | EGFR

Product Information

• Catalog No.: B0084-286627
• CAS No.: 183320-51-6
• Molecular Formula: C21H22ClN3O4
• Molecular Weight: 415.874
• Purity: > 95%

Source

Original product source