Emapunil

Overview

Exhibits high affinity for TSPO in rat whole brain (Ki = 0.297 nM), and high potency against human and rat glial TSPO (IC50 values are 2.73 and 3.04 nM respectively). Displays no noticeable binding to a number of other receptors, transporters or ion channels. Also displays anxiolytic and antidepressant effects in rodent models, without inducing benzodiazepine-like adverse effects.

Application

Products > Drug Discovery > Inhibitor | Products > Drug Discovery > Inhibitor | Neurological Disease | TSPO

Product Information

• Catalog No.: B0084-388916
• CAS No.: 226954-04-7
• Molecular Formula: C23H23N5O2
• Molecular Weight: 401.46
• Purity: >98%

Source

Original product source