AP1903

Overview

AP1903 is a lipid-permeable tacrolimus analogue with homodimerizing activity. Dimerizer drug AP1903 homodimerizes an analogue of human protein FKBP12 (Fv) which contains a single acid substitution (Phe36Val) so that AP1903 binds to wild-type FKBP12 with 1000-fold lower affinity.

Application

Products > Drug Discovery > Inhibitor | Products > Drug Discovery > Inhibitor | Inflammation / Immunology | FK506-binding proteins (FKBPs)

Product Information

• Catalog No.: B1370-462662
• CAS No.: 195514-63-7
• Molecular Formula: C78H98N4O20
• Molecular Weight: 1411.63
• Purity: 0.98

Source

Original product source