Larotaxel

Overview

Larotaxel is a semi-synthetic derivative of the taxane 10-deacetylbaccatin III with potential antineoplastic activities. Larotaxel binds to tubulin, promoting microtubule assembly and stabilization and preventing microtubule depolymerization, thereby inhibiting cell proliferation. As it represents poor substrate for P-glycoprotein-related drug resistance mechanisms, this agent may be useful for treating multi-drug resistant tumors. Larotaxel penetrates the blood brain barrier. Source summary: Larotaxel is a research-use chemical compound for life science studies, suitable as a small-molecule reagent and biochemical research material.

Application

Products > Drug Discovery > Inhibitor | Products > Drug Discovery > Inhibitor | Inflammation / Immunology | Apoptosis Inducer

Product Information

• Catalog No.: B2693-244933
• CAS No.: 156294-36-9
• Molecular Formula: C45H53NO14
• Molecular Weight: 831.912
• Storage: Store at -20°C
• Solubility: Soluble in Chloroform (Slightly), Ethyl Acetate (Slightly), Methanol (Slightly)

Source

Original product source