BMS 986020

Overview

BMS 986020 is a high-affinity lysophosphatidic acid receptor 1 (LPA1) antagonist with an IC50 value less than 300 nM for human LPA1 expressing CHO cells. It inhibits bile acid and phospholipid transporters with IC50s of 4.8 µM, 6.2 µM, and 7.5 µM for BSEP, MRP4, and MDR3, respectively. BMS 986020 is used for the treatment of idiopathic pulmonary fibrosis (IPF).

Application

Products > Drug Discovery > Inhibitor | Products > Drug Discovery > Inhibitor | Neurological Disease | LPL Receptor

Product Information

• Catalog No.: B2693-292060
• CAS No.: 1257213-50-5
• Molecular Formula: C29H26N2O5
• Molecular Weight: 482.5
• Purity: ≥98%
• Solubility: Soluble to ≥ 64 mg/mL in water.

Source

Original product source