K-7174 dihydrochloride

Overview

K-7174, one of proteasome inhibitory homopiperazine derivatives, exhibits a therapeutic effect, which is stronger when administered orally than intravenously, without obvious side effects in a murine myeloma model. Moreover, K-7174 kills bortezomib-resistant myeloma cells carrying a β5-subunit mutation in vivo and primary cells from a patient resistant to bortezomib.

Application

Products > Drug Discovery > Inhibitor > Other Inhibitors | Products > Drug Discovery > Inhibitor

Product Information

• Catalog No.: B2693-463577
• CAS No.: 191089-60-8
• Molecular Formula: C33H50Cl2N2O6
• Molecular Weight: 641.67
• Purity: >98%

Source

Original product source