CMPD101 (Standard)

Overview

CMPD101 (Standard) is the analytical standard of CMPD101 ( HY-103045 ). This product is intended for research and analytical applications. CMPD101 is a potent, highly selective and membrane-permeable small-molecule inhibitor of GRK2/3 with IC 50 of 18 nM and 5.4 nM, respectively. CMPD101 exhibits less selectively against GRK1, GRK5, ROCK-2 and PKCα with IC 50 s of 3.1 μM , 2.3 μM, 1.4 μM and 8.1 μM, respectively. CMPD101 can be used for the study of heart failure.

Application

Products | Products > Signaling Pathways > Cell Cycle/DNA Damage | Products > Signaling Pathways > TGF-beta/Smad | Products > Signaling Pathways > Others | Products > Signaling Pathways > Stem Cell/Wnt | Products > Signaling Pathways > GPCR/G Protein | Products > Signaling Pathways > Cytoskeleton | Products > Signaling Pathways > Epigenetics | Products > Research Areas > Cardiovascular Disease | Products > Signaling Pathways > Reference Standards | Products > Signaling Pathways > G Protein-coupled Receptor Kinase (GRK) | Products > Signaling Pathways > PKC | Products > Signaling Pathways > ROCK

Product Information

• Catalog No.: HY-103045R
• CAS No.: 865608-11-3
• Molecular Formula: C24H21F3N6O
• Molecular Weight: 466.46
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source