ML218 (Standard)

Overview

ML218 (Standard) is the analytical standard of ML218 ( HY-103309 ). This product is intended for research and analytical applications. ML218 is a potent, selective and orally active T-type Ca2+ channels (Cav3.1, Cav3.2, Cav3.3) inhibitor with IC 50 s of 310 nM and 270 nM for Cav3.2 and Cav3.3, respectively. ML218 inhibits the burst activity in subthalamic nucleus (STN) neurons. ML218 has no significant inhibition of L- or N-type calcium channels, KATP or hERG potassium channels. ML218 can penetrate the blood-brain barrier.

Application

Products | Products > Signaling Pathways > Others | Products > Signaling Pathways > Membrane Transporter/Ion Channel | Products > Signaling Pathways > Neuronal Signaling | Products > Research Areas > Neurological Disease | Products > Signaling Pathways > Reference Standards | Products > Signaling Pathways > Calcium Channel

Product Information

• Catalog No.: HY-103309R
• CAS No.: 1346233-68-8
• Molecular Formula: C19H26Cl2N2O
• Molecular Weight: 369.33
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source