SB-328437 (Standard)

Overview

SB-328437 (Standard) is the analytical standard of SB-328437 ( HY-103363 ). This product is intended for research and analytical applications. SB-328437 is a potent, selective non-peptide CCR3 antagonist with an IC 50 of 4.5 nM. SB-328437 can inhibit eosinophil migration induced by eotaxin, eotaxin-2, and monocyte chemotactic protein-4. In addition, SB-328437 can sensitize 5-FU ( HY-90006 )-resistant gastric cancer cells. SB-328437 can also reduce the recruitment of neutrophils to the lungs and pulmonary inflammation during acute inflammation. SB-328437 can be used in the research of inflammation-related diseases.

Application

Products | Products > Signaling Pathways > Others | Products > Signaling Pathways > GPCR/G Protein | Products > Signaling Pathways > Immunology/Inflammation | Products > Signaling Pathways > Apoptosis | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Immunotherapy | Products > Research Areas > Cancer > Cancer Drug Resistance | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Research Areas > Inflammation/Immunology | Products > Signaling Pathways > Reference Standards | Products > Signaling Pathways > CCR | Products > Signaling Pathways > Thymidylate Synthase

Product Information

• Catalog No.: HY-103363R
• CAS No.: 247580-43-4
• Molecular Formula: C21H18N2O5
• Molecular Weight: 378.38
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source